I need a publish-ready, 6,000-word scholarly review that explores how leptin links hypertension and chronic kidney disease. The manuscript must draw on cutting-edge evidence—at least half of the references should be from the past five years—and weave together the following threads: • Hypertension: how leptin shapes blood-pressure regulation, stimulates the sympathetic nervous system, and alters vascular integrity. • Chronic kidney disease: leptin’s direct effects on renal function, its role in inflammation / fibrosis, and its promise as a diagnostic or prognostic biomarker. To illustrate the narrative, please create three visuals: 1. A clear pathway diagram of leptin signalling relevant to both cardiovascular and renal systems. 2. A comparison table summarising key recent studies. 3. A concise statistical chart that spotlights the most compelling leptin-related data. Deliver a Microsoft Word manuscript with the figures and tables embedded, plus separate high-resolution source files (PowerPoint, Illustrator, Excel, or similar) so I can edit them later. All citations should be fully formatted and gathered in a reference list at the end; plagiarism-checking software must show 0 % overlap apart from properly quoted text. Acceptance criteria • ≥6,000 words of main text (excluding abstract, references, legends). • Minimum two visuals; three preferred as described above. • ≥50 % of references dated 2019-2024. • Clear, critical synthesis of the selected leptin mechanisms with no unsupported claims. If you have firsthand experience with biomedical reviews, systematic searches (PubMed, Scopus) and figure design, I’m ready to collaborate immediately.